Multiple Molecular Forms of Malic and Lactic Dehydrogenases during Development

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Multiple Molecular Forms of Malic and Lactic Dehydrogenases during Development*

Lactic dehydrogenase has been shown to exist in mulbiple molecular forms within a single tissue in several different species (2-15). It is now fairly well established that the lactic dehydrogenase molecule is a tetramer composed of four subunits and that there are two types of these subunits (16, 17). The subunits may combine in all possible combinations of four to yield five different tetramer...

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Multiple Molecular Forms of Malic and Lactic Dehydrogenases during Development.

Lactic dehydrogenase has been shown to exist in mulbiple molecular forms within a single tissue in several different species (2-15). It is now fairly well established that the lactic dehydrogenase molecule is a tetramer composed of four subunits and that there are two types of these subunits (16, 17). The subunits may combine in all possible combinations of four to yield five different tetramer...

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Lactic and malic dehydrogenases in the developing chick embryo.

A study of the activity and distribution of glutamic dehydrogenase in various tissues of the developing chick embryo has recently been made (Solomon, 1957). It was found that glutamic dehydrogenase showed marked fluctuations of activity in certain tissues at various stages of development. However, as only relatively low amounts of the enzyme were found in all tissues of the chick embryo and fow...

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Microdetermination of alpha-keto acids with special reference to malic, lactic, and glutamic dehydrogenases in brain.

Previous studies have indicated marked differences in the quantitative distribution of a number of enzymes, as well as other substances, in various histologically distinct areas of the nervous system (l-4). An earlier method (2) for MDH, LDH, and GDH’ in brain required 0.3, 1.5, and 10 y of brain, dry weight, respectively, for the determination of these enzymatic activities. Some of the histolo...

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The Lactic Dehydrogenases of Yeast

Until about 1957 the L(+)-lactic dehydrogenase of aerobic cells was the only enzyme concerned with lactate oxidation known to occur in yeast. At that time, essentially simultaneously and independently, four laboratories discovered the existence of a second lactic dehydrogenase in yeast, which, in distinction to the L enzyme, occurred in anaerobic cells and reacted with ferricyanide but not cyto...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1964

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)51699-9